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The MariTide Phase 2 data presented in November 2024 were highly significant: MariTide demonstrated robust weight loss at 52 weeks with no plateau meaning continued weight loss trajectory at the end of the study period, unlike semaglutide and tirzepatide which show plateau effects and significant improvements in cardiometabolic parameters
This makes Retatrutide the first medication to achieve surgical level weight loss through pharmaceutical intervention alone
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While Zepbound is a branded medication, many people access the same active ingredient, tirzepatide, through other means
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