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In this process, the molecule binds to the receptor, and together form a complex which triggers its endocytosis into the EC
The researchers did some pretty cool endocrine testing looking at GnRH pulsatility at the start of the study and after six months of taking 2g/day of ALC, a GnRH test to look at LH and FSH response to GnRH, and a TRH test (I have no idea what that is)
Animal studies on semaglutide use during early pregnancy have been linked to severe fetal developmental abnormalities as well as embryo-fetal death
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