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The current study provides support for these findings in a real-world clinical setting, demonstrating that tirzepatide was associated with greater weight reduction than semaglutide in a patient population treated for obesity managementrather than for glycaemic control
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Each receptor system has its own adaptation timeline, its own threshold for side effects, and its own contribution to the overall metabolic response
The newer, longer-acting versions like Ozempic and Wegovy were approved more recently (Ozempic in 2017, Wegovy in 2021), but theyve been studied in large clinical trials involving thousands of patients over several years
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