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Below are some evidence-based strategies: Adequate nutrition and protein intake : Sufficient nutrition and dietary protein should be a priority to help preserve muscle mass, particularly in combination with a structured strength training program

These clinical findings also noted the normalization of fasting glucose levels, baseline reductions in insulin doses, and improvement in preexisting insulin resistance

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SELECT Trials Groundbreaking Results In 2023, in a landmark finding, the SELECT trial showed that adults with overweight or obesity but without diabetes, who had previously experienced a heart attack, stroke and/or had peripheral artery disease, taking semaglutide had a 20% reduction in major adverse cardiac events such as heart attacks and strokes compared to those on placebo over the course of 3 years