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Warning signs that should prompt immediate medical evaluation include: Sudden, severe pain in the right upper abdomen or epigastrium Pain radiating to the right shoulder blade or between shoulder blades Nausea and vomiting, especially with abdominal pain Fever or chills accompanying abdominal discomfort Jaundice (yellowing of skin or eyes) Clay-colored stools or dark urine Persistent indigestion or bloating after fatty meals Biliary colicthe classic gallstone symptomtypically presents as episodic right upper quadrant pain lasting 30 minutes to several hours, often triggered by fatty food consumption

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