common side effects semaglutide Effects: vs Serious Symptoms Ozempic side-effects & management: Ozempic

Food intake, body weight, and sweetness preferences over the menstrual cycle in humans

The trials also showed that a proportion of patients treated with tirzepatide experienced significant categorical improvements in OSA severity, with some moving from severe to moderate, moderate to mild, or achieving AHI levels below diagnostic thresholds

As GLP-1Rs are expressed in multiple brain regions, and GLP-1RAs such as liraglutide and lixisenatide can penetrate the blood-brain barrier, liraglutide and exendin-4 can be vagus-dependent or independent in the suppression of the food intake (176)

Last Updated: October 26, 2025 QUICK ANSWER: The 3 most common side effects are: Nausea, diarrhea and constipation