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The evidence has been largely RNA- and protein-based with increased concentrations of interleukin (IL)-4, tumor necrosis factor (TNF)- , soluble TNF receptor 1 (sTNFR1), and soluble IL-2 receptor consistently reported in BD compared to healthy controls [67, 68]
They also act on the brains reward circuits, including those involved with eating, which is one of the mechanisms that may decrease interest in alcohol
Endogenous GH release is pulsatile, with multiple peaks across a 24-hour period
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