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Phase-2 trials did report some benefits of ipamorelin in the condition, but the results were not deemed clinically significant within 7-10 days of therapy, leading to discontinuation of trials [9, 10]

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This dual-pathway mechanism differs fundamentally from single-hormone GLP-1 agents, making its interaction profile distinct

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Combined with reduced appetite from GLP-1 and GIP activation, Retatrutide supports fat loss from multiple angles

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