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49 Hoffer, L
A 2025 systematic review reported 7 of 12 maintained improvement beyond 6 months
NAD+ Clinical Evidence Context Most published human RCT evidence on NAD+ uses oral precursors (NR and NMN), not direct injectable NAD+
The GLP-1 medication semaglutide has been shown to be effective and safe across a broad population of people with overweight and obesity, leading to 10-20% weight loss which is usually needed to see the benefits
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