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The high price of brand-name GLP-1 medications is one of the biggest challenges for patients seeking obesity treatment (BMI 30 or more), overweight (BMI 27 or more), and type 2 diabetes mellitus
Vagus nerve stimulation (VNS) itself reshapes the microbiome: reducing gut inflammation via the cholinergic anti-inflammatory pathway, reinforcing tight junctions, and promoting anti-inflammatory species (e.g., more SCFAs producers like Faecalibacterium)
Dry mouth with semaglutide often appears alongside other oral symptoms
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