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Oral administration increased plasma GLP-1 levels compared with water during an intraperitoneal glucose tolerance test, and ileal administration reduced plasma DPP4 activity and increased the ratio of active GLP-1 to total GLP-1 (Reference Ishikawa, Hira and Inoue69) in rats
Baartscheer, A
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The liver fat advantage is more pronounced, with retatrutide achieving 82% reduction compared to more modest figures for tirzepatide
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