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Furthermore, multiple changes in the composition of the gut microbiota of individuals with PD have been identified ( Porphyromonas , Prevotella , and Corynebacterium ), a decrease in SCFA producers (e.g., Faecalibacterium , Roseburia ), and an increase in bacteria commonly used for their probiotic properties ( Lactobacilli and Bifidobacteria ) (127)

Mice showed a significant preference for the nicotine-paired compartment, which was reversed by exendin-4 administration (p 0.05) [21]

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