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Direct effects on isolated pancreatic cells Study of possible direct effects of GLP-1 on acini began with the discovery of biologically active peptides in Gila monstor venom (33, 34) and the identification of a specific receptor for Exendin-4 on guinea pig isolated pancreatic acini that increased the production of cAMP (93, 94)
La L-Taurina y la L-Carnitina pueden desempear un papel en el metabolismo y la funcin cardaca, mientras que la Coenzima Q10 es conocida por su capacidad para apoyar la produccin de energa celular, lo que puede ser beneficioso para el corazn
Additionally, metformin has demonstrated anti-inflammatory effects through the inhibition of IL-18 expression, which is linked to alterations in the intestinal microbiome (Lee et al., 2019)
