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The overproduction of 5-oxoproline exceeds the capacity of 5-oxoprolinase, and 5-oxoproline therefore accumulates in body fluids and is excreted in the urine
(2025) GFAP has recently gained prominence as a sensitive biomarker of astroglial activation in AD
doi: 10.1016/S0140-6736(21)00213-0 234 WildingJPHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al
Specifically, among the 15,264 females on GLP-1 drugs, 1.62% were diagnosed with breast cancer during the study, compared to 2.47% of the 96,382 females who did not use GLP-1 medications
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