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The discover of 4-I[( S )-2-(3-Chloro-phenyl)-2-hydroxy-ethlamino]-3-(4-methyl-6-morpholin-4-yl-1 H -benzoimidazol-2-yl)-1 H -pyridin-2-one (BMS-536924): an inhibitor of IGF-1R kinase with in vivo antitumour activity

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