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This difference was achieved without any change in food intake, suggesting the weight loss came from metabolic changes rather than appetite suppression
In addition, the main transcription factor of iron metabolism, iron response element binding protein 2 (IREB2), could enhance the FTL and FTH1 expression and decrease ferrous ion concentrations, thereby inhibiting erastin-induced ferroptosis (Gammella et al., 2015)
Glutathione is believed to inhibit the activity of tyrosinase, thereby reducing melanin synthesis and resulting in lighter and brighter skin
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