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Moreover, in recent studies, chemogenetic stimulation of brainstem GIPR was also shown to suppress food intake while activating conditioned taste avoidance responses 13

This includes establishing a consistent sleep schedule, creating a comfortable sleep environment (cool, dark, and quiet), and avoiding screens for at least one hour before bedtime

Kllberg, J

However, due to its indicated short half-live, GLP-1 peptide is an unattractive therapeutic agent on itself, which stimulated the quest for GLP-1 based compounds with better bioavailability