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Esta citocina induce la expresin de TGF- por las clulas de Kupffer, promoviendo la activacin de las CEH, las cuales comienzan la produccin de componentes de la matriz extracelular, que de manera desregulada dan lugar a la progresin de eventos fibrticos94 (fig
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LikelyWell-controlled human studies have demonstrated the likely existence of this interaction
(Each state determines its own age of majority, which can be different for different activities.) Persons under the age of 17 may, however, donate blood for their own use, in advance of scheduled surgery or in situations where their blood has special medical value for a particular patient such as a family member
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