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Semaglutide is a long-acting GLP-1 (glucagon-like peptide-1) receptor agonist, structurally modified from native GLP-1 with a fatty-acid side chain that enables reversible albumin binding extending its half-life to approximately one week and enabling once-weekly dosing regimens studied extensively in clinical trials
Sud D, Sharma S, Dhiman R
The gap is temperature and storage information
In the Phase 1 multiple-ascending dose (MAD) study, VK2735 achieved up to 8.2% mean weight loss at day 28 for the highest dose (100 mg)
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