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Its activity profile is best understood as systems-level polypharmacology rather than single-receptor agonism: published research has documented effects on nitric oxide system signalling, growth-factor receptor expression (including VEGF receptor 2 and growth-hormone receptor), dopamine and serotonin pathway markers, and angiogenic factor regulation

Fa Ren, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Implications of the Growing Popularity of Weight-Loss Drugs In this section, we review five different potential implications of the growing popularity of weight-loss drugs and how these could impact a range of different sectors and companies

Getting onto it is not an approval