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No large clinical trials have established a direct link between GLP-1 medications and acne improvement
An autopsy study revealed a higher prevalence of coronary microvascular rarefaction, microscopic fibrosis, and hypertrophy in HFpEF patients [25]
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Recent studies have found that increased level of GLP-1 in the hippocampus restores GABA and reverses this neurotoxic effect by reducing oxidative stress through the SIRT1/Nrf2/HO-1 pathway, promoting autophagy through the AMPK/mTOR pathway, and alleviating hippocampal apoptosis by inactivating pro-apoptotic kinase GSK-3 (Arab et al., 2023)
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