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Though the absolute risk of GLP-1 related aspiration during intubation is still low, case studies of large volume emesis in patients who fasted 20 hours have been concerning enough to prompt the American Society of Anesthesiology to issue a guidance suggesting holding GLP-1 agonists prior to elective intubations4,5
Conclusion Protein is one of the most important nutrients to prioritize while taking GLP1 medications
Because retatrutide includes GLP-1 agonism (which semaglutide was providing) plus GIP and glucagon agonism, the transition should not result in loss of appetite suppression during the switch
Panganamala et al, 1986
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