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The emergence of oral GLP-1s, once-monthly injectables, dual- and triple-receptor targets and combination therapies has enhanced patient convenience, improved adherence and broadened clinical utility, bringing healthcare practitioners more options for individualized treatment

Mechanisms of oxidative stress have been implicated in the pathogenesis of psychiatric disorders (31)

Synthesis is primarily hindered due to the inhibition of the mTOR signaling pathway (manifested as downregulation of PI3K/Akt/mTORc1 activity), leading to reduced protein synthesis [37]

For example, the thyroid hormones triiodothyronine and thyroxine are released through thyroid stimulating hormone dependent Ca 2+ signaling [133]