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Over 8 weeks, mean body weight in this cohort (50 adults) decreased from 73.69 7.73 kg at baseline to 67.36 7.87 kg at Week 8 (mean reduction: 6.33 kg
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More specifically the accelerated GDH flux (push+pull) induced by troglitazone can be demonstrated using 15N amino labeled glutamine as shown in Figure 5
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