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OA03.03 Datopotamab deruxtecan (Dato-DXd
SGLT-2is can directly reduce body weight by increasing urinary glucose excretion (Tahrani et al., 2016), whereas the consequent increase in water and energy loss may leading to higher energy usage and an increased appetite ( In addition, studies have shown that both GLP-1RAs and SGLT-2is can control blood pressure in T2DM (Sun et al., 2015
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