The results shown by the present study strongly suggest that NAC administration inhibited ethanol-induced oxidative stress (GSSG/GSH ratio) activating the Nrf2-ARE system, which is in line with a report that an analog of NAC, NACA, attenuated the oxidative stress induced by a traumatic brain injury in rats via the same antioxidant system (Zhou et al., Whether an activation of xCT transporter function due to an increased substrate availability and/or an increased xCT expression plays a role in the NAC-induced reduction of hippocampal GSSG/GSH ratio, the administration of the xCT inhibitor SZ was expected to reduce or block such an effect of NAC
Li Y, Gong F, Guo S, Yu W, Liu J (2021) Adonis amurensis is a promising alternative to Haematococcus as a resource for natural esterified (3 S, 3 S)-astaxanthin production
However, it is unclear whether this growth could cause cancer or exacerbate existing tumors
Cells were washed with cold PBS and total proteins were extracted with RIPA buffer containing Halt inhibitors (Thermofisher, MA)