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Las dosis de semaglutida de 0.5 mg y 1 mg proporcionan adecuada exposicin sistmica sobre el rango de peso corporal de 40-198 kg evaluado en los estudios clnicos
This effect was inhibited by the GLP-1 antagonist exendin (939), suggesting that OXM may act through the GLP-1 receptor (GLP-1R) to regulate food intake
25 Luse M.A., et al., Nitrosation of CD36 regulates endothelial function and serum lipids
However, concerns exist regarding the impact of GLP-1 RAs on lean mass, particularly with respect to true skeletal muscle mass
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