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The additive effects of combination SGLT2i and GLP-1RA therapy on HbA 1c and weight outcomes have been observed in randomized controlled trials (RCTs), nonrandomized trials, and real-world observational studies
While the supplements have a milder effect than the drug, they are an excellent choice for those who: Do not want to go on the drug Discontinued the drug due to side effects Want to buffer the side effects of the drug Nutrients that Stimulate GLP-1 Production Probiotic Species: Akkermansia Mucinophilia generates propionate, a short chain fatty acid, and a protein called P9, both of which induce GLP-1 production Clostridium butyricum produces butyrate, which stimulates GLP-1 Bifidobacterium infantis Produces acetate and lactate, which feed the two strains mentioned above, naturally boosting GLP-1 production Bifidobacterium longum increases short chain fatty acids and normalizes leptin, the satiety hormone Lactobacillus plantarum increases short chain fatty acids, normalizes leptin, and decreases inflammation Berberine: Like GLP-1 medications, Berberine has a multitude of metabolic benefits
Additionally, incorrect storage can increase the risk of side effects or adverse reactions
A warning that ignores that is just noise
