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The identification of these alternative immune checkpoints highlights the need for multi-targeted immunotherapeutic approaches that nanomedicine platforms are uniquely positioned to deliver ( Figure 1 )
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[19] [21] The compounds targeted in this manner by GSTs encompass a diverse range of environmental or otherwise exogenous toxins, including chemotherapeutic agents and other drugs, pesticides, herbicides, carcinogens, and variably-derived epoxides
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