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Methods: Time trade-off (TTO) and a visual analog scale (VAS) were used to elicit PWS caregivers values for 3 fixed health states for a standardized patient described with (1) untreated PWS, (2) PWS with controlled obesity, and (3) PWS with controlled obesity and hyperphagia

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"Scientific Opinion on the substantiation of health claims related to L-lysine and immune defence against herpes virus (ID 453), maintenance of normal blood LDL-cholesterol concentrations (ID 454, 4669), increase in appetite leading to an increase in energy intake..." EFSA Journal

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