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While the first drug in this class, exenatide (Byetta), was approved by the FDA in 2005, more recent drugs like semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound) outperform the older drugs in the class and other anti-obesity medications
However, the association with hemorrhagic and ischemic strokes was not statistically significant
Clinical validation Even though several earlier studies on different stimuli-responsive hybrid nanomaterials demonstrated encouraging outcomes in both in vitro and in vivo investigations of wound healing and tissue regeneration, issues still need to be resolved before applying them in clinical settings
