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That means we have no formal evidence on whether lower doses are effective, safe, or provide any long-term health benefits
In a pre-specified extension cohort restricted to participants with a BMI of at least 35, average weight loss reached 30.3% at 104 weeks
Regular check-ups are required to monitor progress and medication effectiveness
And they generally demonstrate favorable safety profiles compared to conventional immunosuppressants, though long-term data in autoimmune populations remains limited for most of these compounds
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