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Individual results may vary.
SURMOUNT-MAINTAIN (Horn 2026, 112 weeks): continued top dose -21.9% vs 5 mg step-down -16.6% vs placebo -9.9%, rescue therapy 8/25/67%: Aronne JAMA 2024
Goal: Support cellular energy metabolism, mitochondrial function and DNA-repair pathways by replenishing NAD+ goals pursued in research and wellness, not established for injectable NAD+ in humans [5] [6]
Some people notice improvement in energy or other symptoms within weeks, while nerve-related symptoms can take longer
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