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10.1038/nrendo.2013.136 34 BenetL
But for most patients seeking effective weight loss treatment, semaglutide represents the current standard of care
Principally, GLP-1 induces glucose-dependent insulin secretion from pancreatic -cells, 10,11 decreases plasma glucagon concentrations, 11 and delays gastric emptying
Additionally, a weight loss of more than 25% was achieved in 40.4% of patients receiving CagriSema, compared to 16.2% of patients receiving semaglutide 2.4 mg, 6% of patients receiving cagrilintide 2.4 mg and 0.9% of patients receiving placebo
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