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So, in addition to breast cancer and acute myeloid leukemia, what our research shows is that there is an association between GLP-1 use and a reduction in liver cancer, pancreatic cancer, gastric cancer and bile duct cancer (cholangiocarcinoma). Shaping the future of medicine: Lasting impact with worldwide implications By translating and expanding on these findings, Jones aims to drive improvements in health and cancer care outcomes

The significant difference determination under 503A is patient-specific and must be made and documented by the prescribing practitioner

Lillys oral GLP-1, orforglipron, demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines in successful Phase 3 trial

A 56-week trial included 422 patients with BMI30 kg/m 2 or BMI27 kg/m 2 with dyslipidemia and/or hypertension (non-diabetic)