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Some patients report that symptoms, including sleep disturbances, may fluctuate following dose increases

Psychology & Health, 33(8), 10141027

It has been found that a decline in the expression of PPAR is associated with advanced MASLD and liver fibrosis (Francque et al

Thus, our results support conducting preclinical studies of semaglutide (and other GLP1R agonist) on THC and randomized clinical trials to evaluate the therapeutic benefits of semaglutide in CUD in individuals with obesity or T2D as well as in patients with CUD who dont have these co-morbid conditions