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A classical drug is like a key in a lock, it has one target receptor and binds there

For instance, in HER2-positive breast cancer, a phase II/III trial (NCT02213744) investigated MM-302, liposomal doxorubicin targeted to HER2, combined with trastuzumab, aiming to achieve dual HER2 blockade and improved tumor targeting

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Results are usually subtle and temporary, making topical formulations more suitable for daily skincare maintenance rather than treating stubborn pigmentation or uneven tone