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Theyd still be losing money, at least in the short term
Drug regimen simplicity is an important clinical consideration, particularly in patients receiving multiple medications for the treatment of T2DM and related comorbidities
The STEP-9 trial showed patients with knee osteoarthritis taking semaglutide experienced marked improvements in pain scores along with significant weight reduction 39
The second class is inhibitors of the GLP-1 degrading enzyme, dipeptidyl pepitidase IV (Sitagliptin and related drugs) which can be given orally and increase the plasma level of GLP-1 and other peptides degraded by DPP-4
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