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Think of it as less goes in, less comes out. Fewer bowel movements can be normal ( even as few as three per week ), but experiencing hard stool, difficulty passing stool, bloating, abdominal pain, or incomplete evacuation would be considered constipation
History SLU-PP-332 was developed through research efforts focused on estrogen-related receptors (ERRs), a family of orphan nuclear receptors that regulate cellular metabolism and mitochondrial function
It is also in the process of being investigated for a variety of other purposes
PMID 23609496
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