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Ozcan et al., 2018)

The Annals of Pharmacotherapy , vol

In fibrosarcoma and osteosarcoma models, ketotifen combined with pegylated liposomal doxorubicin (PLD) or pegylated liposomal coencapsulated alendronate-doxorubicin (PLAD) plus anti-PD-1 antibody improved antitumor responses, increased cytotoxic CD8+ T cell and CD4+ T helper cell infiltration, and Treg numbers