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The STEP trials, which enrolled thousands of patients, documented injection site reactions in approximately 35% of participants, making them uncommon but not unheard of
The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
As of 2024, it is in Phase 3 trials for both obesity and type 2 diabetes
Pharmacological inhibition of GIPR with anti-GIPR antibodies prevented BW gain in DIO mice and obese cynomolgus monkeys 33
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