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It is important to mention that the follow-up duration of Wegovy is only 3 years, whereas other GLP-1 RA medications were studied for 5 years

19,20,22 A third subgroup consisted of head-to-head studies that compared ALC with another active pharmacological agent (n=2)

15 Incretins are gut hormones released into the bloodstream following food consumption that enhances insulin secretion in pancreatic -cells and help decrease high blood glucose levels

This second incretin is produced by enteroendocrine L cells, which are diffusedly distributed in the distal gut mucosa of ileum and colon (25, 26) [ Figure 1 Section A]