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Appetite suppression and weight loss occur predominantly through central GLP-1 receptor activation
Potential concerns Some things worth considering: Cancer risk
In the rats with infrarenally occluded inferior caval vein, the left ovarian vein is rapidly presented as the major pathway (Figure 7)
Theoretical concerns are not proof of harm, but they identify areas off-target SAM effects, signalling-pathway impacts, and uncharacterised interactions that require study before any conclusion about human safety could be drawn
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