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Abstract Heart failure (HF) remains one of the cardiovascular diseases (CVDs) associated with a high unmet medical need due to high morbidity and mortality rates and lack of efficacious interventions

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The deciding factor is always the same: if the vial will be used once, sterile water is clean, simple, and sufficient its only when multi-dose use comes into play that bacteriostatic water becomes the necessary standard

A2A-D2 receptor-receptor interaction modulates gliotransmitter release from striatal astrocyte processes