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For instance, Ex-4 injections into the lateral hypothalamus (LH) and dorsomedial hippocampus have been shown to suppress ethanol intake (Tuesta et al., 2017)
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Epidemiological studies showed that genes contribute to the vulnerability of multiple CNS disorders, such as major depressive disorders (MDD), schizophrenia and substance use disorders with heritability respectively of 3142%, 6480%, and 2379% [10,11,12,13]
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