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These findings suggest that secondary tumors may arise as a potential side effect of pharmacological ferroptosis induction, underscoring the need for long-term experiments to assess this possibility in suitable animal models
Other work has demonstrated that increasing AMPK signaling, or restricting mTOR activity, also increases Tmem formation in mice (130)
Pregnant women are advised to ensure adequate folate intake to promote neural tube development, which occurs in the early stages of pregnancy
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