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This phase is where compliance with your protocol becomes especially important
In patients treated with semaglutide, median duration of nausea was 8 days, vomiting 2 days, diarrhoea 3 days, and constipation 47 days. Over the 68-week trial period nausea occurred in 43.9% of patients (16.1% placebo)
Others plateau on semaglutide and do significantly better after switching
Research from the SURMOUNT clinical trial program found that cardiovascular adverse events, including palpitations, occurred in 25% of participants, with the majority resolving spontaneously within the first month of dose stabilization
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