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Bitter vegetables such as chicory, dandelion, radicchio, and artichoke contain sesquiterpene lactones that stimulate bile secretion and activate intestinal TAS2R bitter-taste receptors, generating a combined sensory and hormonal signal that triggers CCK release and colonic reflex activity ( Dietary fats, particularly those rich in monounsaturated and polyunsaturated fatty acids, such as EVOO, nuts, and avocado, further enhance CCK-mediated gallbladder contraction and bile secretion
With over $300 million already spent, actuaries projected the number approaching $1 billion by 2026 if coverage continued unchanged
is particularly important because it directly examines semaglutide use in older adults with T2DM with an explicit focus on sarcopenia and provides relatively long-term outcomes [60]
Tirzepatide and cancer risk in individuals with and without diabetes: a systematic review and meta-analysis
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