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patients with T2D under treatment with dulaglutide (n = 76)
Unlike simpler single-receptor agonist peptides, retatrutide is a complex 39-amino-acid synthetic peptide
In a large RCT involving obese and prediabetic individuals, tirzepatide significantly delayed the onset of T2DM compared with placebo across multiple doses, with sustained benefits observed during long-term follow-up
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