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Hathaway JT, Shah MP, Hathaway DB, et al
Key highlights Semaglutide is a glucagon-like peptide-1 receptor agonist that works on GLP-1 receptors in the body to manage blood glucose levels and lose weight by delaying gastric emptying and reducing appetite
Here's what you'll actually see prescribed for weight loss or weight-related indications in 2026: A few things worth noting
And people gain the weight back when they come off it. Costs for five of the GLP-1 drugs Ozempic, Mounjaro, Wegovy, Zepbound, and Saxenda topped $300 million for Boston-based Blue Cross last year, more than double what it spent in 2023
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